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Treating to target in Crohn's disease

Bret A. Lashner, MD

Director, Center for Inflammatory Bowel Disease
Professor of Medicine
Cleveland Clinic
Cleveland, OH



Treatment goals for Crohn's disease are evolving beyond symptom control towards deep remission, which encompasses clinical remission together with mucosal healing. The ultimate goals are to prevent bowel damage, reduce long-term disability and maintain normal quality-of-life. This Case Consult discusses a treat-to-target approach, with increased monitoring and tighter control of symptoms and inflammation.

This activity has been designed to meet the educational needs of gastroenterologists and registered nurses involved in the care of patients with inflammatory bowel disease (IBD).

Release date: January 19, 2015

Learning objectives

After completing this activity, the participant should be better able to:

  • Describe the use of mucosal healing as a treatment target for Crohn's disease
  • Provide appropriate care and counsel for patients and their families.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

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